C. Gregory Elliott, MD, FCCP, and editorialist David Langlaben, MD, join CHEST Podcast Editor, D. Kyle Hogarth, MD, FCCP, to discuss the recent research of Dr. Elliott et al that determined the genetic mutations responsible for pulmonary capillary hemangiomatosis (PCH), a rare cause of pulmonary hypertension. The EIF2AK4 mutuations were found using exome sequencing.