Cystic fibrosis transmembrane conductance regulator modulators are bringing new hope to many patients with CF. But what do physicians and patients need to know about the latest CFTC regulator modulator therapies?
Susan Millard, MD, is a pediatric pulmonlogist at Helen DeVos Children's Hospital in Grand Rapids, Mich. In an audio interview, Dr. Millard discusses the new FDA-approved combination therapy of elexacaftor, texacaftor, and ivacaftor (Trikafta). It's a trio that could make a significant difference for the roughly 90% of patients with at least one F508del mutation of the CFTC regulator gene.
Dr. Millard outlines which patients are candidates for the combination therapy, what physicians and patients can expect with Trikafta use, and how the drug affects patients' use of other CF therapies. She also outlines the steps physicians should take before starting patients on the therapy, and what side effects to watch for during treatment.
