Dr Nichola Conlon from Nuchido talks about why simply taking NAD is not enough to solve your NAD deficiency. Have you ever asked yourself why NAD levels go down as we age? After all, our cells are built to recycle NAD - so why on earth is everyone so deficient? In this episode I dig deep into the issues of NAD deficiencies due to aging or disease and, TIME+ a supplement that may just provide the missing link in restoring youthful NAD levels.
To try TIME+ for yourself:
Nuchido.com
Promo Code: Longevity10 saves you 10%
Episode Notes:
4:51 All about Nichola, she looks 22 but definitely isn’t, she has an 11 year old daughter. What she got her PHD in and more about her background.
6:40 Nutrient transport and how it actually gets transferred into the cell
9:30 How drug companies go about creating a solution. Single target approach
10:10 Biology is very complex, every pathway is connected, and expecting a drug to only affect one thing is not ideal.
11:00 The body has backup plans, the body is resilient
12:00 Why drugs have side-effects
14:00 The multi target approach and why it’s important
16:00 How aging and drug development came together
18:00 How Nuchido was born
20:24 How this supplement addresses NAD in the cell (totally unique)
21:00 Why just hoping that NAD gets to right place is not ideal
22:10 NAD is estimated to be involved in 500 different reactions in the body
23:00 When maintenance and repair pathways get turned down
24:05 The cycles of NAD that we want
25:55 How damage to the cells/aging correlate with NAD
26:15 By the time we’re 20, we’ve already lost half the NAD we’re born with, but there’s good news!
27:00 Why NAD levels naturally decline, and certain diseases decrease NAD
27:35 Chronic fatigue syndrome
27:57 The people who will notice the greatest benefits from Time+
29:50 Lifestyle factors that affect your NAD levels
31:00 Mitochondria, lyme disease and even COVID-19
34:00 How MOST supplements boost NAD through precursors NMN and NMR
37:00 The problem with relying on precursors, and why the root cause is so important
37:57 Enzymes and NAD\
38:20 Why in some cases taking precursors is actually worse than not taking them
39:50 Methylation and why you may need to take a methyl donor if you take precursors
40:50 The importance of NAD and NADH balance
41:30 Instead of just adding to the factory, fix the factory so that it works well
46:00 NMMT
48:00 The optimal ratio of NAD and NADH
52:00 Can NAD+ be found in nutrition?
57:30 Ingredients in Time+ and why you shouldn’t be worried if you accumulate high levels of zinc
59:20 Why green tea is so amazing, egcg and methylation
1:01:24 Why parsley is so important
1:09:00 Why whole systems are so important
1:11:40 Senescent cells and why you should pay attention to this!
Disclaimer: This podcast is intended for information purposes only and none of the information presented should ever be taken as medical advice. Consult with your physician or medical provider before making any changes to your diet or lifestyle (including starting new supplements).
