This podcast presents an approach to hemolytic anemia in children. In it, the listener will learn to define hemolytic anemia, explain the pathophysiology, describe the clinical manifestations, list relevant investigations and outline the management of a child with hemolytic anemia. This podcast was created by Prachi Shah, a medical student at the University of Alberta, in collaboration with Dr. Aisha Bruce, a pediatric hematologist at the Stollery Children’s Hospital in Edmonton.